JENKINS, Cheryl

Cheryl Jenkins

Research Interests

  • Host-parasite interactions
  • Microbial pathogenesis and vaccine development
  • Microbial diversity and evolution
  • Proteomics and protein structure
  • Molecular test development

Background

Cheryl is a Principal Research Scientist leading a molecular biology laboratory within the Microbiology and Parasitology section at EMAI. She has 15 years’ experience in molecular biology with a focus on microbial pathogenesis, diagnostic test development, proteomics and genomics.

She has over 80 works published in peer-reviewed journals such as Open Biology, Infection and Immunity, Veterinary Microbiology, Molecular Microbiology, Parasites & Vectors and the Proceedings of the National Academy of Sciences USA.

Qualifications

  • BSc. (Hons I)
  • PhD (University of Qld)

Current projects

Current major projects centre on using genomic tools to better understand disease epidemiology and virulence mechanisms and to inform vaccine design. Areas of interest include bovine theileriosis, mycoplasmology and aquatic animal health. Future work aims to use genomics, proteomics and microbiomics as a basis for computational technologies such as reverse vaccinology and risk-based tools for disease prediction based on network analysis. Cheryl collaborates extensively with Universities and research agencies.

Recent publications

Seymour, L. M., Deutscher, A. T., Jenkins, C., Kuit, T. A., Falconer, L., Minion, F. C., Crosset, B., Padula, M., Dixon, N. E., Djordjevic, S. P. and Walker, M. J. (2010) A processed multi-domain Mycoplasma hyopneumoniae adhesin binds fibronectin, plasminogen and swine respiratory cilia. J. Biol. Chem. 285: 33971-8.

Deutscher, A. T., Jenkins, C., Minion, F. C., Padula, M., Seymour, L. M., Dixon, N. E, Walker, M. J. and Djordjevic, S. P. (2010). Repeat regions R1 and R2 in the P97 paralog Mhp271 of Mycoplasma hyopneumoniae bind heparin, fibronectin and porcine cilia. Mol. Micro. 78: 444-58.

Wilton JL, Jenkins C, Cordwell SJ, Falconer L, Minion FC, Oneal DC, Djordjevic MA, Connolly A, Barchia I, Walker MJ and Djordjevic SP (2009) Mhp493 (P216) is a proteolytically processed cilium and heparin binding protein of Mycoplasma hyopneumoniaeMol. Micro. 71: 566-82.

Jenkins C, Samudrala R, Geary SJ and Djordjevic SP (2008) Structural and functional characterization of an organic hydroperoxide resistance (Ohr) protein from Mycoplasma gallisepticumJ. Bact. 190: 2260-16.

Jenkins C, Geary SJ, Gladd M and Djordjevic SP (2007) The Mycoplasma gallisepticum OsmC-like protein MG1142 resides on the cell surface and binds heparin. Microbiology 153: 1455-1463.

Schlesner H, Jenkins C and Staley JT (2007) Phylum Verrucomicrobia: A phylogenetically heterogeneous bacterial group. In M. Dworkin et al., (eds) The Prokaryotes 3rd Edition. Springer, New York, USA.

Oertli G, Jenkins C, Ward NL, Rainey FA, Stackebrandt E and Staley JT (2007) The Genera Prosthecomicrobium and Ancalomicrobium.  In M. Dworkin et al., (eds) The Prokaryotes 3rd Edition. Springer, New York, USA.

Jenkins C, Wilton JL, Minion FC, Falconer L, Walker MJ and Djordjevic SP (2006)  Identification of heparin-binding regions within the cilium adhesin (P97) of Mycoplasma hyopneumoniaeInfect Immun 74: 481-487.

Staley JT, Bouzek H and Jenkins C (2005) Eukaryotic signature proteins of Prosthecobacter dejongeii and Gemmata sp. Wa1-1 as revealed by in silico analysis. FEMS Microbiol Lett 243: 9-14.

Jenkins C, Rainey FA, Ward NL and Staley JT (2005) Prosthecomicrobium. In G. Garrity (ed.), Bergey's Manual of Systematic Bacteriology, 2nd Edition. Springer, New York, USA.

Jenkins C and Staley JT (2005) Ancalomicrobium. In G. Garrity (ed.), Bergey's Manual of Systematic Bacteriology, 2nd Edition. Springer, New York, USA.

Staley JT, Jenkins C and Konopka AE (2005) Ancylobacter. In G. Garrity (ed.), Bergey's Manual of Systematic Bacteriology, 2nd Edition. Springer, New York, USA.

Chistoserdova L, Jenkins C, Kalyuzhnaya M, Marx CJ, Lapidus A, Vorholt JA, Staley J, and Lidstrom ME (2004) The enigmatic planctomycetes may hold a key to the origins of methanogenesis and methylotrophy. Mol Biol Evol 21: 1234-41.

Jenkins C, Samudrala R, Anderson I, Hedlund BP, Petroni G, Michailova N, Pinel N, Overbeek R, Rosati G and Staley JT (2002) Genes for the protein tubulin discovered in members of the bacterial genus, Prosthecobacter. Proc Natl Acad Sci USA. 99: 17049-17054.

Jenkins C, Kedar V and Fuerst JA (2002) Gene discovery within the planctomycete division of Domain Bacteria using sequence tags from genomic DNA libraries. Genome Biol 3: research0031.

Wang J, Jenkins C, Webb RI and Fuerst JA (2002) Isolation of Gemmata-like and Isosphaera-like planctomycete bacteria from soil and freshwater. Appl Env Microbiol 68: 417-422.

Jenkins C and Fuerst JA (2001) Phylogenetic analysis of evolutionary relationships of the planctomycete division of the domain Bacteria based on amino acid sequences of elongation factor-Tu. J Mol Evol 52: 405-418.

Professional association and activities

  • Undertook post-doctoral training at the University of Washington, Seattle, USA
  • Adjunct fellowship at the University of Technology Sydney
  • Member of the AUSGEM Science Committee
  • Member of the Board of Directors of the International Organisation for Mycoplasmology

Contact details

Email: cheryl.jenkins@dpi.nsw.gov.au