CLAYTON, Ed

Ed Clayton

Research interests

  • Ruminant physiology and nutrition.
  • Forage conservation.
  • Animal health and behaviour.
  • Meat quality and omega-3 fatty acids.
  • Omega-3 fatty acids and reproduction in sheep.
  • Examining possible health benefits of omega-3s.

Background

Ed Clayton completed a Bachelor of Rural Science and a PhD in ruminant nutrition at University of New England (UNE) before commencing work with the NSW Department of Primary Industries in 1999. He conducted industry-based commercial research between 2000-2002 in parasitology and nutrition at The Oaks, near Camden. During this time Ed became involved with monogastric nutrition and the effects of nutrition on behaviour. In line with the nutrition and behaviour theme, he was employed as a research fellow in a child and adolescent intensive care psychiatric unit at the John Hunter Hospital in Newcastle.

Ed was then employed as a Research Fellow in the Nutraceuticals Research Group at the University of Newcastle, researching the effects of omega-3 fatty acids on a range of disease models in humans including risk factors for cardiovascular disease, before taking up the position of Livestock Research Officer with NSW DPI* in 2007. Ed's research examines the links between fatty acids in the diets of sheep and cattle with their reproduction as well as the health status of beef and lamb.

*NSW Department of Primary Industries was formed on July 1, 2004 through an amalgamation of NSW Agriculture, NSW Fisheries, State Forests of NSW and the NSW Department of Mineral Resources.

Qualifications

  • B.Rural Science. – University of New England 1995
  • Ph.D Ruminant Nutrition – University of New England 1999

Current projects

  • Examining omega-3 fatty acids in silage versus fresh forage.
  • Examining the relationship between omega-3 fatty acids and reproductive efficiency in sheep.
  • Examining the relationship between fatty acids in the diet of sheep and cattle and the amount of omega-3 in beef and lamb.
  • Developing NIR calibrations for the analysis of volatile fatty acids, lactic acid and long-chain fatty acids in silage.

Recent publications

Refereed journal articles

Clayton EH, Wilkins JF, Friend MA (2016). Intergenerational effects of omega-6 fatty acids: 1. The reproductive rate of Border Leicester x Merino ewes is influenced by the diet fed to their dams around conception. Animal Production Science In Press: Accepted for publication 07/10/2015.

Clayton EH, Wilkins JF, Friend MA (2016). Intergenerational effects of omega-6 fatty acids: 2. Intergenerational effects of omega-6 fatty acids: 2. Preliminary evidence for the influence of diet fed to dams at conception on the sex ratio of lambs born to their daughters. Animal Production Science In Press: Accepted for publication 10/09/2015.

Clayton EH, Wilkins JF, Friend MA (2016). Increasing the proportion of female lambs by feeding Merino ewes a diet high in omega-6 fatty acids around mating. Animal Production Science 56 (7): 1174-1184. (IF = 1.218).

Clayton EH, Wilkins JF, Friend MA (2016). Increased proportion of female lambs by feeding Border Leicester x Merino ewes a diet high in omega-6 fatty acids. Animal Production Science 56 (5): 824-833. (IF = 1.218).

Alvarenga TIRC, Copping KJ, Han X, Clayton EH, Meyer RJ, Rodgers RJ, McMillen IC, Perry VEA, Geesink G (2016). The influence of peri-conception and first trimester dietary restriction of protein in cattle on meat quality traits of entire male progeny. Meat Science In Press: Accepted for publication 02/06/2016.

Alvarenga TIRC, Chen Y, Lewandowski P, Ponnampalam EN, Sadiq S, Clayton EH, van de Ven R, Perez JRO, Hopkins DL (2016). The expression of genes encoding enzymes regulating fat metabolism is affected by maternal nutrition when lambs are fed algae high in omega-3. Livestock Science 187 (1): 53-60. (IF = 1.897) doi:10.1016/j.livsci.2016.02.013

Robertson SM, Clayton EH, Friend MA (2015). Reproductive performance of ewes grazing lucerne during different periods around mating. Animal Reproduction Science 162: 62-72.

Robertson SM, Clayton EH, Morgan B, Friend MA (2015). Reproductive performance in ewes fed varying levels of cut lucerne pasture around conception. Animal Reproduction Science 158 (1): 75-85. (IF = 1.897) doi: 10.1016/j.anireprosci.2015.05.001

Clayton EH, Wilkins JF, Refshauge G, Friend MA (2015). Lower concentration of n-3 in the red blood cells and plasma of lambs when their dams were fed a diet high compared with low in n-6 fatty acids at joining. Lipids 50 (9): 883-893.

O’Keeffe PA, OrchardD, OrchardBA, Piltz JW, Clayton EH (2014). Native Australian shrub legume species may provide an alternative feed source for livestock. Animal Production Science 55(10): 1090-1096. 01/08/2014. (IF = 1.218).

Clayton EH, Lamb TA, Refshauge G, Kerr MJ, Bailes KL, Friend MA and Hopkins DL (2014). Differential response to an algae supplement high in DHA mediated by maternal peri-conceptional diet - Intergenerational effects of omega-6 fatty acids. Lipids 49 (8): 767-775. (IF = 2.557).

Hopkins DL, Clayton EH, Lamb TA, van de Ven RJ, Refshauge G, Kerr MJ, Bailes KL, Lewandowski P and Ponnampalam EN (2014). The impact of supplementing lambs with algae on growth, meat traits and oxidative status. Meat Science 98 (2): 135-141. (IF = 2.231).

White BH, Clayton EH and Friend MA (2014). The effect of mechanical processing of wheaten straw on intake and rumen parameters following grain feeding in sheep. Animal Production Science 54 (9): 1455-1459. (IF = 1.218).

McGrath S, Bhanugopan M, Dove H, Clayton EH, Virgona J and Friend MA (2014). Mineral supplementation of lambing ewes grazing dual-purpose wheat. Animal Production Science 55 (4): 526-534. (IF = 1.218).

Croft IA, Clayton EH and Cusack PMV (2014) Health and production of feedlot cattle following supplementation with urea-molasses in starter pens. Australian Veterinary Journal 92 (5): 166-170. (IF = 0.918).

Gulliver CE, Friend MA, King BJ, Wilkins JF and Clayton EH (2013). A higher proportion of female lambs when ewes were fed oats and cottonseed meal prior to and following conception. Animal Production Science 53 (5): 464-471. (IF = 1.218)doi: 10.1071/AN12279

Gulliver CE, Friend MA, King BJ, Robertson SM, Wilkins JF and Clayton EH (2013). Increased prostaglandin response to oxytocin in ewes fed a diet high in omega-6 polyunsaturated fatty acids. Lipids 48 (2): 177-183. (IF = 1.419) doi: 10.1007/s11745-012-3745-3

Clayton EH, Gulliver CE, Piltz JW, Taylor RD, Blake RJ and Meyer RJ (2012). Improved extraction of saturated fatty acids but not omega-3 fatty acids from sheep red blood cells using a one-step extraction procedure. Lipids 47 (7): 719-727. (IF = 1.419)

Gulliver CE, Friend MA, King BJ and Clayton EH (2012). The role of omega-3 polyunsaturated fatty acids in reproduction of sheep and cattle. Animal Reproduction Science 131 (1-2): 9-22. (IF = 1.897) doi:10.106/j.anireprosci.2012.02.002.

Packer EJ, Clayton EH and Cusack PMV (2011). Bodyweight gain in cattle treated with monensin and grazing lush pasture. Australian Veterinary Journal 89 (9): 338-345. (IF = 0.918)doi: 10.1111/j.1751-0813.2011.00802x

Stone, T. E., McMillan, M., Hazelton, M. and Clayton, E. H. (2010). Swearing and verbal aggression in an inpatient setting: implications for mental health nursing practice. Perspectives in Psychiatric Care 47 (7): 194-203. (IF = 1.000) doi:10.1111/j.1744-6163.2010.00295.x

Hanstock, T. L., Clayton, E. H. and Mallet, P. E. (2010). Increased plasma D-Lactic acid associated with impaired memory in rats. Physiology and Behavior 101 (5): 653-659. (IF = 2.561). doi:10.1016/j.physbeh.2010.09.018

Clayton EH, Hanstock TL, Kable CJ, Hirneth SJ, Garg ML and Hazell PL (2009) Reduced mania and depression in juvenile bipolar disorder associated with long-chain omega-3 polyunsaturated fatty acid supplementation. European Journal of Clinical Nutrition 63 (8): 1037-1040.

Clayton EH, Hanstock TL and Watson JF (2009) Estimated intakes of meat and fish by children and adolescents in Australia and comparison with recommendations. British Journal of Nutrition 101 (12): 1731-1735.

Clayton EH, Hanstock TL, Kable CJ, Hirneth SJ, Garg ML, and Hazell PL (2008e) Long-chain omega-3 polyunsaturated fatty acids in the blood of children and adolescents with juvenile bipolar disorder. Lipids 43 (11): 1031-1038.

Clayton EH, Hanstock TL, Garg ML, and Hazell PL (2007) Long-chain omega-3 polyunsaturated fatty acids in the treatment of psychiatric illnesses in children and adolescents. Acta Neuropsychiatrica 19 (2): 92-103.

Garg ML, Blake RJ, Clayton EH, Munro IA, Macdonald-Wicks L, Singh H, and Moughan PJ (2007a) Consumption of an n-3 polyunsaturated fatty acid-enriched dip modulates plasma lipid profile in subjects with diabetes type II. European Journal of Clinical Nutrition 61 (11): 1312-1317.

Garg ML, Blake RJ, Wills R, and Clayton EH (2007b) Macadamia nut consumption modulates favourably risk factors for coronary artery disease in hypercholesterolemic subjects. Lipids 42 (6): 583-587.

Clayton EH and Blake RJ (2005) Possible errors in the analysis of lactic acid and volatile fatty acids in the gastrointestinal tract of pigs and chickens. Applied and Environmental Microbiology 71 (4): 2206 - 2207.

Refereed Conference Proceedings

Krebs GL, Street SH, Dutton A, Clayton EH and Piltz JW (2014). Nutrient digestibility in Merino, Dorset and Dorper/Damara cross sheep fed diets of differing quality. Proceedings of the Australian Society of Animal Production. 30: 67.

Robertson SM, Clayton EH, King BJ, Knott S, Morgan B and Friend MA (2014). Lucerne pasture ad libitum after day 7 post insemination may increase embryo mortality in ewes. Proceedings of the Australian Society of Animal Production. 30: 66.

Hand EJ, Friend MA, Clayton EH (2014). Timing of oestrus and lamb sex ratio when ewes were fed diets differing only in omega-3, omega-6 or saturated fatty acid content prior to mating In "Annual Scientific Meeting of the Endocrine Society of Australia and the Society for Reproductive Biology." 24th - 27th August, p 63, Melbourne, Vic.

Fowler SM, Schmidt H, Clayton EH, Bailes KL, Wynn PC and Hopkins DL (2014a). Predicting fatty acid composition of ovine Longissimus thoracis lumborum using Raman spectroscopy. Proceedings of the Australian Society of Animal Production. 30: 54.

Fowler SM, Schmidt H, Clayton EH, van de Ven R, Bailes KL, Wynn PC and Hopkins DL (2014b). Predicting fatty acid composition of lamb loin using Raman spectroscopy. In "60th International Congress of Meat Science and Technology", Punta Del Este, Uruguay

Clayton, E. H., Wilkins, J. F., King, B. J., Meyer, R. J. and Friend, M. A. (2013). Can we increase the proportion of female lambs by feeding oats at joining? In "Proceedings of the 54th Annual Conference of the Grassland Society of Southern Australia Inc." pp. 97-102, Albury, NSW.

Clayton, E. H., Gulliver, C. E., Wilkins, J. F., King, B. J., Meyer, R. J. and Friend, M. A. (2012). Increasing the proportion of female lambs by supplementary feeding oats high in omega-6 fatty acids at joining. In "Proceedings of the 27th Annual Conference of the Grassland Society of NSW Inc." pp. 107-113, Wagga Wagga, NSW.

Clayton, E. H., Gulliver, C. E., Meyer, R. J, Piltz, J. W. and Friend, M. A. (2011). Reduced red blood cell omega-3 fatty acid concentrations after inclusion of oat grain in the diet of ewes for 52 days. Recent Advances in Animal Nutrition in Australia 18: 172.

Clayton, E. H., Hanstock, T. L., Hirneth, S. J., Kable, C. J. and Hazell, P. L. (2011). Omega-3 fatty acid concentrations in depression in children and adolescents. World Congress of Asian Psychiatry 17: S61.

Hirneth, S. J., Hazell, P. L., Hanstock, T. L. and Clayton, E. H. (2011). Evaluation of treatment outcomes from an Australian juvenile bipolar disorder clinic. Bipolar Disorders 13 (X): XXX. (IF = 4.442)

Clayton, E. H., Piltz, J. W. and Wynn, P. C. (2010). Increased rumen biohydrogenation of omega-3 and omega-3 fatty acids in silage compared with fresh forage. Australasian Medical Journal 1 (1): 136. Doi 10.4066/AMJ.2010.209.

Clayton, E. H., Hazell, P. L., Hirneth, S. J. and Hanstock, T. L. (2010). Omega-3 fatty acids as a potential neuroprotective agent for mental health issues in young people. Australian and New Zealand Journal of Psychiatry In Press: Presented at the Australasian Society for Psychiatric Research Conference, Sydney, Australia, 2-4 December 2010.

Clayton, E. H., Watson, J. F., Hazell, P. L., Hirneth, S. J., Kable, C. J. and Hanstock, T. L. (2010). The Gastrointestinal Symptoms Evaluation for Nutritional Supplements (GSENS): Preliminary development and validation. Australasian Medical Journal 1 (1): 71. Doi 10.4066/AMJ.2010.209.

Clayton, E. H., Wynn, P. C., Mailer, R. J., and Piltz, J. W. (2010). Total lipid and fatty acid profiles in fresh and ensiled forages grown in Australia. In "Proceedings of the Australian Society for Animal Production" (R. C. Dobos, P. L. Greenwood and J. V. Nolan, eds.), Vol. 28, pp. 56. Australian Society for Animal Production, Armidale, NSW.

Griffiths, N., Piltz, J. W., Clayton, E. H., Meyer, R. and Richards, S. (2010). Effect of heating on feed quality of hay. In. Proceedings of the NSW Grasslands Society Conference, Ed. 28-29 July 2010, Dubbo, NSW, pp. Available online:

Gulliver, C. E., Piltz, J. W., Friend, M. A. and Clayton, E. H. (2010). Improving the omega-3 status of sheep by feeding silage. Australasian Medical Journal 2 (1): 131. Doi 10.4066/AMJ.2010.209.

Gulliver, C. E., Piltz, J. W., Friend, M. A. and Clayton, E. H. (2010). Reducing inflammation in sheep by feeding silage high in omega-3. Australasian Medical Journal 2 (1): 131. Doi 10.4066/AMJ.2010.209.

Gulliver, C. E., Friend, M. A., King, B. J., Robertson, S. M., and Clayton, E. H. (2010). Feeding high omega-3 diets to crossbred ewes: effect on time to oestrus. In "Proceedings of the Australian Society for Animal Production" (R. C. Dobos, P. L. Greenwood and J. V. Nolan, eds.), Vol. 28, pp. 94. Australian Society for Animal Production, Armidale, NSW.

Gulliver, C. E., Friend, M. A., Robertson, S. M., Martin, G. B., Clayton, E. H., and King, B. J. (2010). Short-term lupin feeding: can it decrease ovulation rate in Merino ewes? In "Proceedings of the Australian Society for Animal Production" (R. C. Dobos, P. L. Greenwood and J. V. Nolan, eds.), Vol. 28, pp. 100. Australian Society for Animal Production, Armidale, NSW.

Gulliver, C. E., Friend, M. A., King, B. J., Robertson, S. M., and Clayton, E. H. (2010). Longer time to oestrus in ewes fed a high omega-3 diet. In "61st Annual Meeting of the European Association for Animal Production", Vol. 16, pp. 113. Wageningen Academic Publishers, The Netherlands, Heraklion, Crete Island, Greece.

Clayton, E. H., Piltz, J. W., Mailer, R. J. and Wynn, P. C. (2009). Higher omega-6:omega-3 fatty acid ratio in silage compared with fresh forage. Recent Advances in Animal Nutrition in Australia 17: 172.

Clayton EH, Piltz JW and Wynn PC (2009) Increased rumen biohydrogenation of omega-3 and omega-3 fatty acids in silage compared with fresh forage. Australasian Medical Journal 1 (1): 136.

Clayton EH, Watson JF, Hazell PL, Hirneth SJ, Kable CJ and Hanstock TL (2009) The Gastrointestinal Symptoms Evaluation for Nutritional Supplements (GSENS): Preliminary development and validation. Australasian Medical Journal 1 (1): 71.

Clayton EH, Piltz JW, Mailer RJ and Wynn PC (2009) Higher omega-6:omega-3 fatty acid ratio in silage compared with fresh forage. Recent Advances in Animal Nutrition in Australia 17: 172.

Clayton EH, Hirneth SJ, Hazell PL, Kable CJ and Hanstock TL (2009) Validity of a paediatric quality of life questionnaire for participants with juvenile bipolar disorder. Bipolar Disorders 11 (7): 784.

Hanstock TL, Hirneth SJ, Hazell PL, Kable CJ and Clayton EH (2009) Improvement in digit span in juvenile bipolar disorder following supplementation with long chain omega-3 polyunsaturated fatty acids. Bipolar Disorders 11 (7): 781.

Hanstock TL, Hirneth SJ, Hazell PL, Kable CJ and Clayton EH (2009) Digit span improvement following long chain omega-3 polyunsaturated fatty acids supplementation: A preliminary study. Australasian Medical Journal 1 (1): 131.

Hirneth SJ, Hazell PL, Hanstock TL and Clayton EH (2009) Evaluation of treatment outcomes from an Australian juvenile bipolar disorder clinic. Bipolar Disorders 11 (7): 780.

Hirneth S, Hazell P, Hanstock T, and Clayton EH (2009) Juvenile bipolar disorder: Preliminary outcomes from a treatment evaluation study. In. Proceedings of the Australasian Society for Psychiatric Research Conference, Canberra, ACT pp. 144.

Parry K, Cusack PJ, Packer EJ and Clayton EH (2009) Increased growth rate in Murray Grey but not Angus steers treated with monensin capsules. In. Proceedings of the NSW Department of Primary Industries Sheep and Beef Conference Ed. Andrews, T.  11-13 November, 2009, Orange, NSW, pp 46. Available online: www.dpi.nsw.gov.au.

Clayton EH, Hanstock TL, Hazell PL, Hirneth SJ, Kable CJ, and Garg ML (2008). Reduced erythrocyte concentration of omega-3 polyunsaturated fatty acids in children and adolescents with bipolar disorder. Asia Pacific Journal of Clinical Nutrition 17 (Suppl 3): S61.

Clayton EH, Piltz JW, Zhao J, and Wynn PC (2008) Maximising omega-3 available for meat through production of high quality silage. Asia Pacific Journal of Clinical Nutrition 17 (Suppl 3): S116.

Other publications

Griffiths N, Piltz JW, Clayton EH, Meyer R and Richards S (2011). Turning up the heat on feed quality. Farming Ahead 230.

Clayton EH, Hanstock TL, Hirneth SJ, Kable CJ, Garg ML and Hazell PL (2009) Omega-3 supplementation in juvenile bipolar disorder: Is it effective? In. “Bipolar Disorder in Young People Forum”, Black Dog Institute, Randwick, Australia, October 12, 2009. Available at: www.blackdoginstitute.org.au.

Piltz JW, Hackney BF and Clayton EH (2009) Silage for cattle - Gaining extra production. Australian Society of Animal Production Local Meeting, Holbrook NSW, Wednesday 8th April, 2009, pp 1-5.

Clayton EH and Piltz JW (2009) Comparison of analytical services provided by competitors of the NSW Department of Primary Industries Feed Quality Service (FQS). NSW Department of Primary Industries Report. 35 pp.

Clayton EH and Piltz JW (2009) Promoting healthy lean red meat. Agriculture Today, Thursday January 26, 2009, Rural Press, Richmond.

Piltz JW, Bailes KL, Clayton EH and Kaiser AG (2008) Reducing feedout losses due to aerobic spoilage (heating). Dairy Australia Project DAN 11905 - Final Report. NSW Department of Primary Industries, Wagga Wagga, May 2008, 28 pp.

Clayton EH and Piltz JW (2008). Forage diets for finishing. Agriculture Today, Thursday June 26, 2008, Rural Press, Richmond.

Clayton EH, Meyer R, Piltz JW, Bailes KL and McKiernan WA (2007) NIR prediction of digestibility using calibrations based on either the pepsin cellulase or Tilley and Terry in vitro wet chemistry assays - Summary of the methods used to calibrate the NIR for the analysis of digestibility for the NSW Department of Primary Industries Feed Quality Service (FQS). NSW Department of Industries Report, 71 pp.

Clayton EH, Phang M, and Garg ML (2006b) Milestone Report 4. Influence of consuming functional foods fortified with tomato extract and fish oil on platelet function - Acute and chronic effects. Food Industry Grant - Milestone Report to Campbell Arnotts, 39 pp.

Clayton EH, Phang M, and Garg ML (2006a) Milestone Report 3. Investigation into the effects of tomato serum and long-chain omega-3 fatty acids on ex vivo platelet function in whole blood - Combination acute and chronic effects. Food Industry Grant - Milestone Report to Campbell Arnotts, 32 pp.

Professional associations and activities

  • Member of the technical committee for the World Congress on Oils and Fats held in Sydney September 2009
  • Member of the Australian Society of Animal Production
  • Member of the Australian Fodder Industry Association Quality Evaluation Committee

Fields of research

  • 70204 Animal Nutrition
  • 70206 Animal Reproduction
  • 110104 Medical Biochemistry: Lipids
  • 111714 Mental health
  • 111101 Clinical and Sports Nutrition
  • 110499 Complementary/alternative medicine not elsewhere classified
  • 111716 Preventive Medicine

Australian and New Zealand Standard Research Classification (ANZSRC)

Keyword/phrase list of research interests

  • Ruminant nutrition
  • Ruminant physiology
  • Meat quality
  • Forage conservation

Contact details

Email: edward.clayton@dpi.nsw.gov.au