MARSH, Ian

Ian Marsh

Research interests

  • Molecular diagnosis of genetic disorders in production animals
  • Molecular biology-based research of pathogens that affect terrestrial and aquatic species
  • The development of improved diagnostic tests of pathogens that affect terrestrial and aquatic species

Background

Ian is an animal health research officer focusing on microbiological diseases in production animals. He specialises in molecular biology-based research and the development of improved diagnostic tests of pathogens that affect terrestrial and aquatic species.

In collaboration with the University of Sydney he is investigating improved and enhanced direct diagnosis tests of pathogens that affect terrestrial and aquatic species. With the University of the Sunshine Coast he is leading research exploring Chlamydiosis in production animals.

The majority of his research has focused on Johne’s disease (JD) but other areas his has been active in include; viral diseases of finfish, parasitic diseases of oysters and epidemiological modelling on the effects of exotic disease outbreaks which has resulted in many peer-reviewed journal articles in journals. Ian has worked closely with colleagues on the development of the ANZ Standard Diagnostic Procedures for JD and has made significant contributions to the World Organisation of Animal Health (OIE) chapters on JD and Epizootic haematopoietic necrosis virus.

Qualifications

  • Bachelor of Technology Management (Biotechnology) (First Class Honours) - University of Western Sydney
  • PhD Veterinary Science - University of Sydney

Current projects

  • Collaboration with the University of Sydney: Improved and enhanced direct diagnosis of OJD and BJD from faeces
  • ARC Linkage Project: What role does wildlife play in emergency disease?

Recent projects

  • Development of  the molecular- based microbiological diagnostic capability in the RVL, EMAI.
  • Possibilities for improving the D-PCR test for M. a. paratuberculosis from faeces.
  • QX disease surveillance and window of infection experiment 2006
  • Genomic and proteomic comparative study of the sheep and cattle strains of Mycobacterium avium subsp. paratuberculosis.

Recent publications

Richard J Whittington, Ian B. Marsh, Vanessa Saunders, Irene R. Grant, Ramon Juste, Iker A. Sevilla, Elizabeth J.B. Manning and Robert H.Whitlock 2011Culture Phenotype of Genomically and Geographically Diverse Mycobacterium avium subsp. paratuberculosis Isolated from Different Hosts J. Clin Micro (accepted)

Marsh IB and Whittington RJ (2007) Genomic diversity in Mycobacterium avium: single nucleotide polymorphisms between the S and C strains of M. avium subsp. paratuberculosis and with M. a. avium. Mol Cell Probes 21:66-75.

Marsh IB, Bannantine JP, Paustian ML, Tizard ML, Kapur V, and Whittington RJ (2006) Genomic comparison of Mycobacterium avium subsp. paratuberculosis sheep and cattle strains by microarray hybridization. J Bacteriol 188:2290-3.

Marsh IB*, Bannantine JP, Tizard ML, and Whittington RJ (2005) Genomic and proteomic comparative study of the sheep and cattle strains of Mycobacterium avium subsp. paratuberculosis. In Proceedings of the Eighth International Colloquium on Paratuberculosis, Copenhagen. (Eds: E. J. B. Manning and S. S. Nielsen). Pp.381-392 Madison: International Association for Paratuberculosis.

Marsh I*, Whittington R, Reddacliff L and Eamens G (2005) Hybridisation capture PCR and direct PCR on pooled faecal samples. In Meat and Livestock Australia, Harvest Year Conference 2005, Adelaide (Eds: Unknown). Pp. 21-27. Meat and Livestock Australia.

Whittington RJ, Marsh IB, and Reddacliff LA (2005) Survival of Mycobacterium avium subsp. paratuberculosis in dam water and sediment. Appl Environ Microbiol 71:5304-8.

Marsh IB and Whittington RJ (2005) Deletion of an mmpL gene and multiple associated genes from the genome of the S strain of Mycobacterium avium subsp. paratuberculosis identified by representational difference analysis and in silico analysis. Mol Cell Probes 19:371-84.

Whittington RJ, Marshall DJ, Nicholls PJ, Marsh IB, and Reddacliff LA (2004) Survival and dormancy of Mycobacterium avium subsp. paratuberculosis in the environment. Appl Environ Microbiol 70:2989-3004.

Whittington RJ, Marsh IB, Taylor PJ, Marshall DJ, Taragel C, and Reddacliff LA (2003) Isolation of Mycobacterium avium subsp paratuberculosis from environmental samples collected from farms before and after destocking sheep with paratuberculosis. Aust Vet J 81:559-63.

Marsh IB, Whittington RJ, O'Rourke B, Hyatt AD, and Chisholm O (2002) Rapid differentiation of Australian, European and American ranaviruses based on variation in major capsid protein gene sequence. Mol Cell Probes 16:137-51.

Professional associations and activities

  • Member of the International Association for Paratuberculosis
  • Member of the Australian Association of Veterinary Laboratory Diagnosticians

Contact details

Email: ian.marsh@dpi.nsw.gov.au