History of illness, clinical signs of central nervous system disturbance, biochemical analysis of tissues. In calves, thymic haemorrhages are a frequent finding at necropsy.
In the live animal:
- 100 g of faeces.
- 10 ml EDTA blood tube.
In the dead animal:
- 50 g of kidney, submitted chilled for toxicology.
- Sections of liver and kidney, and whole brain in buffered formalin for histopathology.
Interpretation of lead concentrations (cattle and sheep)
|Sample||Minimum amount||Units||Normal||Possibly toxic||Toxic|
|Kidney (Liver)||50g||mg/kg (wet wt)||< 4||4-25||>25|
|Faeces||100g||mg/kg (wet wt)||<10||10-25||>25|
Kidney lead concentrations below 4 mg/kg are considered non-significant. Higher concentrations should be interpreted on the basis of clinical findings and histopathology.
Faecal lead concentrations below 10 mg/kg are considered non-significant. Higher concentrations could be significant depending on the source of lead.