Also known as hairy shaker disease
Border disease is caused by a Pestivirus (Flaviviridae) infection of the foetus in early pregnancy. Infection of naïve, pregnant ewes can lead to placentitis, foetal death, and abortion. Affected lambs are born 2-3 days prematurely and many die before or at weaning. Surviving hairy shaker sheep remain infected and excrete the virus throughout their lives.
Border disease or hairy shaker disease is a congenital disorder of lambs and outbreaks of infertile ewes and abortion. Affected lambs are undersized with extremely hairy coat and may exhibit involuntary muscular tremors, mainly of the trunk and hind limbs. The nervous signs gradually disappear in surviving lambs within 3-4 months of age. Other affected lambs can have skeletal defects such as dropped pasterns and mandibular brachygnathia.
Diagnosis is supported by history, clinical signs and the demonstration of Pestivirus in affected lambs and antibody in the ewe.
Days of the week test is conducted
Up to 2 weeks for brain samples. Up to 5 days for spinal cord samples.
Pestivirus antibody AGID
Whole blood (red top tube) or foetal fluid
Tuesday & Friday
Pestivirus antigen capture ELISA (PACE)
Whole blood (red top tube), lithium heparin blood (green top tube) or EDTA blood (purple top tube)
Batch tested 2-3 times weekly
Whole blood (red top tube) or EDTA tube (purple top tube)
According to demand
Up to 1 week
Whole blood (red top tube)
Batch tested on Friday
1 Turnaround times are provided as a guide only. For specific information about your submission please contact Customer Service.
Heparinised blood from young animals (under 6 months of age) allows PACE analysis of the buffy coat without interference from maternal antibodies in the serum